Plague illness has 3 possible clinical presentations: bubonic (the most common), pneumonic, or septicemic. The incubation period is typically 1–6 days. In 2017, schools in the Republic of Seychelles were closed and large public gatherings banned in response to a plague outbreak in neighboring Madagascar. For example, during a plague outbreak in India in the 1980s, planes from India were temporarily prevented from landing in Europe, although none of the passengers had symptoms of plague. ![]() pestis while traveling is unlikely.Īlthough travelers’ risk is negligible (no plague cases have been reported among travelers returning to the United States in >40 years), cases of plague can lead to societal disruptions that complicate travel. ![]() The overall risk for travelers is low, and encountering Y. Plague is endemic to rural areas in central and southern Africa, especially eastern Democratic Republic of the Congo, northwestern Uganda, and Madagascar parts of the southwestern United States the northeastern part of South America central Asia and the Indian subcontinent. Less common exposures include handling infected animal tissues (e.g., among hunters and wildlife personnel) inhaling infectious droplets from cats or dogs with plague and, rarely, contact with a patient who has pneumonic plague. pestis transmission usually occurs through the bite of infected rodent fleas. Yersinia pestis, the causative organism for plague, is a gram-negative coccobacillus. A clinical laboratory certified in high complexity testing state health department or contact CDC’s Division of Vector-Borne Diseases (97 Infectious Agent
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